Publications (peer-reviewed)

  • Engels AC, Luc J, Jimenez J, Barrett DW, Connon C, Chowdhury TT, David A, Deprest JA. Tissuepatch is biocompatible and seals iatrogenic membrane defects in a rabbit model. Prenatal Diagnosis 2017 In Press
  • Barrett DW, Kethees A, Thrasivoulou C, Mata A, Virasami A, Sebire NJ, Engels, A, Deprest JA, Becker D, David AL, Chowdhury TT. Trauma induces overexpression of Cx43 in human fetal membrane defects. Prentat Diagn. 2017;37(9):899-906. doi:10.1002/pd.5104
  • Barrett DW, David AL, Thrasivoulou C, Mata A, Becker DL, Engels AC, Deprest JA, Chowdhury TT. Connexin 43 is overexpressed in human fetal membrane defects after fetoscopic surgery. Prenat Diagn. 2016;36(10):942-952. doi: 10.1002/pd.4917. http://onlinelibrary.wiley.com/doi/10.1002/pd.4917/abstract;jsessionid=058DF438B70B419CEA0DFEC85862CFA4.f03t03

  • Tilwani RK, Vessillier S, Pingguan-Murphy B, Lee DA, Bader DL, Chowdhury TT. Oxygen tension modulates the effects of TNFa in compressed chondrocytes. Inflammation Research. 2016;66(1):49-58. DOI: 10.1007/s00011-016-0991-5 http://link.springer.com/article/10.1007%2Fs00011-016-0991-5
  • Peake NJ, Bader DL, Ramachandran M, Vessillier S, Hobbs AJ, Chowdhury TT (2015). C-type natriuretic peptide signalling drives homeostatic effects in human chondrocytes. Biochem Biophys Res Comm. doi:10.1016/j.bbrc.2015.08.08. http://www.sciencedirect.com/science/article/pii/S0006291X15304770

  • Peake NJ, Pavlov AM, D’Souza A, Pingguan-Murphy B, Sukhorukov GB, Hobbs AJ, Chowdhury TT (2015). Controlled Release of C-Type Natriuretic Peptide by Microencapsulation Dampens Proinflammatory Effects Induced by IL-1β in Cartilage Explants. Biomacromolecules doi: 1021/bm501575w. http://pubs.acs.org/doi/abs/10.1021/bm501575w
  • Chowdhury B, David AL, Thrasivoulou C, Becker DL, Bader DL, Chowdhury TT (2014). Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane. Placenta 35(12):1057-64. doi: 10.1016/j.placenta.2014.09.006. http://www.placentajournal.org/article/S0143-4004%2814%2900782-6/abstract
  • Peake NJ, Hobbs AJ, Pingguan-Murphy B, Salter DM, Berenbaum F, Chowdhury TT (2014). Role of C-type natriuretic peptide signalling in maintaining cartilage and bone function. Osteoarthritis Cartilage 22(11):1800-7. doi: 10.1016/j.joca.2014.07.018. http://www.oarsijournal.com/article/S1063-4584%2814%2901191-1/abstract
  • Hossain MA, Chowdhury T, Bagul A (2014). Imaging modalities for the in vivo surveillance of mesenchymal stromal cells. J Tissue Eng Regen Med doi: 10.1002/term.1907. http://onlinelibrary.wiley.com/doi/10.1002/term.1907/abstract
  • Peake N, Su N, Ramachandran M, Achan P, Salter DM, Bader DL, Moyes AJ, Hobbs AJ and Chowdhury TT (2013). Natriuretic peptide receptors regulate cytoprotective effects in an ex vivo human 3D / bioreactor model. Arthritis Research Therapy, 15(4):R76. http://arthritis-research.com/content/15/4/R76
  • Hossain MA, Frampton AE, Chowdhury TT, Morsy M (2013). Biological vascular grafts for hemodialysis access. Expert Rev Med Devices 10(2):171-5. http://informahealthcare.com/doi/abs/10.1586/erd.12.85
  • Parker E, Vessillier S, Pinguaan-Murphy B, Abas W, Bader DL and Chowdhury TT (2013). Low oxygen tension increased FN-f induced catabolic activities – response prevented with biomechanical signals. Arthritis Research Therapy, 15(5):R163. http://arthritis-research.com/content/15/5/R163
  • Tilwani RK, Bader DL and Chowdhury TT (2012). Biomechanical conditioning enhanced matrix synthesis in nucleus pulposus cells cultured in agarase constructs with TGFβ. Journal Functional Biomaterials 3:23-26. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031018/
  • Ramachandran M, Achan P, Bader DL, Salter DM and Chowdhury TT (2011). Biomechanical signals and CNP counteract catabolic activities induced by IL-1β in chondrocyte/agarose constructs. Arthritis Research Therapy. 13(5):R145. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308073/
  • Bader DL, Salter DM and Chowdhury TT (2011). Biomechanical influence of cartilage homeostasis in health and disease. Arthritis. 979032, doi:10.1155/2011/979032. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196252/
  • Lee DA, Brand J, Salter DM, Akanji OO and Chowdhury TT (2011). Quantification of mRNA using real-time PCR and western blot analysis of MAPK events in chondrocyte/agarose constructs. Methods Mol Biol 695:77-97.
  • Akanji OO, Sakthithasan P, Salter DM and Chowdhury TT (2010). Dynamic compression alters NFkB activation and IkB-a expression in IL-1β stimulated chondrocyte/agarose constructs. Inflammation Res. 59(1):41-52.
  • McGlashan SR, Chowdhury TT, Knight MM, Joshi P, Jensen CG, Kennedy S and Poole CA (2010). Chondrocyte cilia incidence and length are mechanosensitive in a duration-dependent manner. Cell Biol Int 34(5):441-6.
  • Chowdhury TT, Schulz RM, Rai SS, Thuemmler C, Wuestneck N, Bader A and Homandberg GA (2010). Biomechanical modulation of collagen fragme nt induced anabolic and catabolic activities in chondrocyte/agarose constructs. Arthritis Research Therapy 12(3):R82.
  • Raveenthiran SP, Chowdhury TT (2009). Dynamic compression inhibits FN-f induced iNOS and COX-2 expression in chondrocyte/agarose constructs. Biomech Model Mechanobiology. 8(4):273-83.
  • Chowdhury TT, Salter DM, Bader DL, Lee DA (2008). Signal transduction pathways involving p38 MAPK, JNK, NFkB and AP-1 in chondrocytes cultured in agarose constructs and subjected to IL-1b and dynamic compression. Inflammation Research 57(7):306-13.
  • Chowdhury TT, Akanji OO, Salter DM, Bader DL, Lee DA (2008). Dynamic compression influences IL-1β induced .NO and PGE2 release by articular chondrocytes via alterations in iNOS and COX-2 expression. Biorheology. 45(3-4):257-274.
  • Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Salter DM, Bader DL, Lee DA (2008). Dynamic compression counteracts IL-1β induced iNOS and COX-2 expression in chondrocyte/agarose constructs. Arthritis Res Ther 10(2):R35.
  • Campbell JJ, Blain EJ, Chowdhury TT, Knight MM (2007). Mechanical loading triggers cortical actin disassembly in articular chondrocytes. Biochem Biophys Res Commun. 361(2):329-34.
  • Chowdhury TT, Bader DL, Lee DA (2006). Combined anti-inflammatory effects of IL-4 and dynamic compression in IL-1β stimulated chondrocyte / agarose constructs. Biochem Biophys Res Commun 339(1):241-7.
  • Chowdhury TT, Appleby, RN, Salter DM, Bader DL, Lee DA (2006). Integrin-mediated mechanotransduction in IL-1β stimulated bovine chondrocytes cultured in agarose constructs. Biomech Model Mechanobiology 5(2-3): 192-201.
  • Chowdhury TT, Bader DL, Lee DA (2006). Dynamic compression counteracts IL-1β induced iNOS and COX-2 activity in human chondrocytes/agarose constructs. Biorheology 43:413-29.
  • Chowdhury TT and Knight MM (2006). Purinergic pathway suppresses the release of .NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression. J Cell Phys 209(3):845-853.
  • Chowdhury TT, Salter DM, Bader DL, Lee DA (2004) integrin-mediated mechanotransduction processes in TGFβ stimulated monolayer-expanded chondrocytes. Biochem Biophys Res Commun 318:873-881.
  • Bryant SJ, Chowdhury TT, Lee DA, Bader DL, Anseth KS (2004). Cross-linking density influences chondrocyte metabolism in dynamically loaded photocrosslinked PEG hydrogels. Ann Biomed Eng 32(3):407-417.
  • Chowdhury TT, Bader DL, Lee DA (2003) Dynamic compression counteracts IL-1β induced release of .NO and PGE2 release by superficial zone chondrocytes cultured in agarose. OA Cartilage 11:688-696.
  • Chowdhury TT, Bader DL, Shelton JC, Lee DA (2003). Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression. Archives Biochem Biophys 417:105-11.
  • Lee DA, Chowdhury TT, Roberts SR, Knight MM, Bader DL (2002). An in vitro investigation of cartilage mechanotransduction. Int J Artificial Organs 35(7):617-61.
  • Chowdhury TT, Bader DL, Lee DA (2001). Dynamic compression inhibits the synthesis of .NO and PGE2 release by IL-1β stimulated chondrocytes cultured in agarose constructs. Biochem Biophys Res Commun 285: 1168-1174.